Together we transform
We deliver complex manufacturing facilities for clients who are advancing science, developing medicine and creating capacity that impact people’s lives. We assemble the best teams in the world to design, build, qualify and commission first-of-a-kind facilities within accelerated timelines with a relentless focus on safety, quality and cost – overcoming challenges no one else can.
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100 +
life sciences projects, representing $50B+ in construction costs
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4 K+
global resources
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20
ISPE Facility of the Year Awards since 2010
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# 1
in pharmaceuticals for 20 years and Top 500 design firm (Engineering News-Record, 2024)
What we do
We’re supporting our biopharma clients to bring innovative products to market at pace. With a relentless focus on safety, quality and cost, our diverse, global teams and Subject Matter Experts (SMEs) deploy an integrated project delivery (IPD) approach and leverage cutting-edge digital tools to deliver ‘first of a kind’ facilities within accelerated timelines. In this rapidly evolving environment, we’re supporting clients to deliver projects in these emerging areas:
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Messenger RNA (mRNA)
mRNA is a rapidly evolving area of medicine with huge potential. United by a sense of shared purpose, we’re working with our biopharma clients, deploying creative thinking and high-level problem solving to accelerate the development and delivery of potentially transformative treatments. The delivery of facilities that are designed for higher production volumes and make treatments accessible to more patients is a crucial step towards revolutionizing modern medicine.
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Cell Therapy
As the commercialization of autologous cell-therapy products gathers pace, wider access is becoming a reality. To ensure more people around the world can access these innovative treatments, we are partnering with clients to overcome operational and regulatory challenges as they scale out production.
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Gene Therapy
With an increasing number of cell and gene therapy products receiving regulatory approval, there is a burning need to deliver projects that support the growth of groundbreaking treatments. We’re working hand-in-hand with clients to provide a flexible approach to facility design that addresses complex challenges as manufacturers ramp up production capacity.
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CDMOs
Contract development and manufacturing organizations (CDMOs) are supporting a seismic shift in Life Sciences, with their highly flexible large-scale facilities increasing production capacity on a massive scale, reducing risk for pharma companies, and guaranteeing hyper-speed project delivery. We’re helping CDMO clients reach these previously unattainable production targets with a flexible approach realized using integrated project delivery (IPD).
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Flexible Facilities
Flexibility played a central role in the response to COVID-19, with solutions providers and Life Sciences companies working together at lightning speed to retro-fit existing facilities for vaccines and treatments. This approach is helping to futureproof the sector, enabling companies to scale manufacturing in response to evolving patient needs, providing fast-tracked access to potentially transformative medicines treatments and therapies for patients globally and addressing patient demand for new treatments and therapies.
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Explore our projects
Our work continues to positively impact millions of lives with significant projects and programs around the globe.
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Fujifilm Diosynth Biotechnologies
Building one of the largest, end-to-end cell culture contract manufacturing facilities in North America so vital medicines and therapies can be delivered with quality, flexibility, speed and consistency at an even larger scale.
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WuXi Biologics Drug Substance Manufacturing Facility
WuXi Biologics’ state of the art biopharmaceutical plant in Dundalk, Ireland is one of the largest single-use bioreactors-based facilities in Europe. Notably, it is also WuXi Biologics’ first greenfield biopharmaceutical facility outside China.
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Spark Therapeutics, Gene Therapy Innovation Center
Jacobs is delivering engineering, procurement and construction management contract for Spark Therapeutics’ new Gene Therapy Innovation Center in the University City area of West Philadelphia. When complete, the multi-story facility will serve as a global center of excellence for gene therapy manufacturing and advance the science of gene therapy.
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Bristol Myers Squibb Large-Scale Cell Culture Manufacturing Facility
Bringing life-saving pharmaceutical treatments to the market for tomorrow.
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Mark Cuban Cost Plus Drug Company Pharmaceutical Facility
Jacobs is proviing engineering services for Mark Cuban Cost Plus Drug Company, PBC’s facility in Dallas, Texas. The facility will provide low-cost versions of high-cost generic drugs.
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Edwards Lifesciences Greenfield Manufacturing Facility
Supplying Europe with critical heart valve technologies just got a bit easier with completion of Edwards Lifesciences’ new Gold LEED-certified manufacturing facility in Ireland’s National Technology Park just outside Limerick. Recipient of the 2022 Irish Construction Excellence Award in the “Industrial Over €15m” category, it was constructed using an Integrated Project Delivery (IPD) procurement approach and innovative digital tools.
Meet some of our team
Read more about the talent who make it happen every day.
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John Noble
Vice President & General Manager, Life Sciences
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Dana Tilley
Vice President, Life Sciences, North America
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Anil Relan
Vice President, Life Sciences, India and Asia
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John Cronin
Vice President, Life Sciences, Europe
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Helga Salling
Vice President, Global Growth & Strategy, Life Sciences
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Lene Bjerregaard
Director of Life Sciences Operations, Denmark
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Julie Vickers
Subject Matter Expert and Lead Process Engineer, Life Sciences
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Peter Cramer
Principal Process Architect
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Todd Rumsey
Senior Process Engineer
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Francesca McBride
Director of Regulatory Compliance
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John Chapman
Senior Architectural Technologist and Subject Matter Expert
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Judith (Judy) Kozak
Director of Commissioning, Qualification and Validation for Life Sciences - North America
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Dhruv Kapoor
Director of Process Engineering, Life Sciences - Conshohocken
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Monika Verma
Senior Principal Architect
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Parimal Trivedi
Lead Piping Engineer
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Priya Unni
Piping Section Manager
Read our latest news
From new project wins and milestones to reports, podcasts and industry insights, discover what we’re up to.
From our newsroom
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News
Jacobs Selected to Support Delivery of $1.2B Expansion of FUJIFILM Diosynth Biotechnologies' Large-Scale Biologics Manufacturing Site
Jacobs (NYSE:J) was selected by FUJIFILM Diosynth Biotechnologies to support delivery of $1.2 billion expansion of an end-to-end, large-scale cell culture contract manufacturing site in Holly Springs, North Carolina. Jacobs was originally selected to support the construction for the FUJIFILM Diosynth Biotechnologies' Holly Springs site, which broke ground in 2021. Jacobs will provide engineering, procurement and construction management services for the site's latest expansion.
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News
Jacobs Opens New Dublin Office and Celebrates 50 Years in Ireland
During the past 50 years, we’ve supported the delivery of award-winning critical infrastructure projects for clients in Ireland – cementing Ireland’s position as a center of excellence for complex advanced manufacturing and R&D and supporting transformational economic growth. To support our continued growth, read about our investment in our new Dublin office.
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News
Setting the Standard for Pharma Facilities of the Future
The Pfizer Biotechnology Center in Hangzhou, China – designed by us – nabbed two ISPE Facility of the Year awards.
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News
Leading With Purpose: A Q&A with Director of Life Sciences Operations for Denmark, Lene Bjerregaard
Leveraging expertise built during her 25-year career, Director of Life Sciences Operations for Denmark, Lene Bjerregaard, is driving sustainable growth at our new Danish base.
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News
Sustainable, Safe and State-of-the-Art: Biocon Biologics’ New Bangalore Facility Receives Recognition
Jacobs-delivered Biocon Biologics’ new flexible facility, one of the largest in India and an honorable mention for Facility of the Year
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Podcasts
Precision Medicine: Tailor-made Treatment
On this episode of If/When, we discussed the topic of precision medicine with Dr. David Fajgenbaum, Assistant Professor of Medicine, Translational Medicine & Human Genetics, University of Pennsylvania and author of the book, Chasing My Cure: A Doctor's Race to Turn Hope Into Action, and Francesa McBride, Director, Regulatory Compliance at Jacobs.
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News
Q&A: Talking with Subject Matter Expert and Lead Process Engineer, Life Sciences, Julie Vickers
Working at the forefront of life sciences, Subject Matter Expert (SME) and Lead Process Engineer Julie Vickers deploys creative thinking and high-level problem solving to turn design concepts into next-generation cell and gene therapy and mRNA facilities. We interviewed Julie about trends in facility design, how mRNA has the potential to transform product delivery and the importance of diverse, inclusive teams to drive innovation.
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Podcasts
Advancing the Facilities of the Life Sciences Industry
Advances in medicine over the past 30 years have extended and improved the quality of life for people around the world. In this episode of Inflection Points, John Noble, Jacobs Vice President and General Manager, Life Sciences talks about the life sciences industry and how integrated project management helps firms get their facilities done on time.
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News
Powering Progress in Life Sciences: A Q&A with Peter Cramer, AIA Subject Matter Expert and Principal Process Architect
With advances in mRNA set to usher in changes in modern medicine, Peter Cramer discusses how we support clients to overcome challenges in this rapidly evolving field and deliver first-of-a-kind projects.
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News
Q&A: Talking with Jacobs’ Ohio AstraZeneca Retrofit Team
We connected with Jacobs’ Lindsay Gerding, Mayme Brusoe and Amy Gardner to talk career, their project with AstraZeneca shaping a potential COVID-19 vaccine and what they enjoy about being part of #OurJacobs. Read more in their Jacobs.com interview.
Our insights
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How Flexibility Can Deliver ATMP’s Potential
With the emergence of new medical treatments and therapies reaching the market, and thousands of new therapies also in preclinical and clinical stages, pharmaceutical manufacturing companies are looking to implement multi-model and flexible facilities. Jacobs’ Julie Vickers, Todd Rumsey, Peter Cramer and Francesca McBride discuss how to determine compatibility and congruence between primary and alternative modalities to deliver products with different manufacturing requirements and deliver transformative medicines to patients, faster.
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Regulatory Considerations for Delivering ATMP Multi-Model Facilities
When it comes to the design and operation of multi-modal facilities, adhering to evolving regulatory requirements across varying jurisdictions is a key consideration. Jacobs’ Francesca McBride discuss the regulatory requirements needed to support the production of the following types of therapies and treatments.
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Our stories
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News
Together We Transform: A Word from John Chapman
Jacobs Senior Architectural Technologist and Subject Matter Expert John Chapman shares the purpose that drives his work in designing manufacturing facilities for pharmaceutical and bio-pharmaceutical products.
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News
Together We Transform: A Word from Judith Kozak
Director of Commissioning, Qualification and Validation for Jacobs Life Sciences North America Judith Kozak shares how a family health scare serves as a daily reminder of the life-changing impact Jacobs has.
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News
Together We Transform: A Word from Dhruv Kapoor
Director of Process Engineering for Jacobs’ Conshohocken Life Sciences operation Dhruv Kapoor shares how enabling access to healthcare in countries all over the world motivates him every day.
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News
Together We Transform: A Word from Monika Verma
Jacobs Senior Principal Architect, Monika Verma, shares a personal story of how her work designing pharmaceutical facilities for research and development and the manufacturing of medicines for people around the world has impacted her personally.
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News
Together We Transform: A Word from Parimal Trivedi
Lead Piping Engineer Parimal Trivedi shares his personal experience of how modern medicine has transformed his family’s life.
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News
Together We Transform: A Word from Priya Unni
Jacobs Piping Section Manager, Priya Unni, weighs in on our culture at Jacobs and how our Life Sciences team inspires her everyday.
In the media
Pharma Manufacturing: How a modular mindset supports ATMP innovation (Peter Cramer)
Pharmaceutical Technology: Overcoming Operational and Regulatory Challenges in Autologous Cell-Therapy Facilities (Francesca McBride)
Pharma Manufacturing: Engineering Angles: A flexible future (Brian Ribnicky)
Pharma Manufacturing: Engineering Angles: Fast-tracking access to treatments (John Noble)
Pharma Manufacturing: Achieving the ‘design one, build many’ paradigm (John Noble)
BioPharm International: Designing Flexible Fill/Finish Facilities (Jorge Ferreira, Lora Zeanchock)
Triangle Business Journal: Fujifilm picks Jacobs Engineering for $2B Holly Springs Project
BioPharm International: Controlling Quality in Aging Facilities
LinkedIn: Together, We Transform (John Noble)
LinkedIn: How The Bio-pharma Sector’s Quest to Combat COVID-19 is Transforming Project Delivery (John Noble)
Irish Building Magazine: Meet Irish Construction Excellence’s Industry Contribution Award Recipient, Jim Hayde (page 116)
Irish Examiner: Cliona Kennedy: Teamwork at Heart of Engineering Projects
Engineers Ireland: Why I Became An Engineer: Elaine Clarke, Process Engineer, Jacobs
Engineers Ireland: Why I Became An Engineer: Katie Kilcoyne, Process Engineer, Jacobs
ICE Awards 2022: Industrial Over €15m - Edwards Lifesciences Greenfield Manufacturing Facility, Limerick
ISPE FOYA 2020: 2020 FOYA Category Winner for Facility of the Future & Overall Winner - Sanofi
ISPE FOYA 2019: 2019 Category Winner for Project Execution - Pfizer