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How can architecture help mitigate risks related to climate change and ensure long-term building resilience?

Meet Brian Cook. With more than 23 years of experience, Brian shapes high‑performance workplaces, life science facilities and global buildings. His work blends innovation, sustainability and human‑centered design.

Brian Cook

With more than two decades of experience delivering complex, high-performance developments, Brian Cook is a seasoned architectural leader in civic, life science and commercial mixed-use design. As technical principal of architecture, laboratory planning and interiors based out of Boston, Massachusetts (MA), Brian drives design excellence and technical innovation for large-scale, multi-phased projects across the U.S. and internationally.

In addition to his technical leadership, Brian plays a pivotal role in business development locally for the Jacobs team in Boston, helping strengthen long-term client relationships and expand the company’s presence in the life science, advanced technology/manufacturing industries.

Brian is widely recognized for his experience in custom building enclosures and complex façades. His leadership spans all phases of project delivery — from early visioning through construction — ensuring precision, quality and alignment with client goals. 

“Design transcends merely conjuring a “big idea” or drafting a “fat pen sketch.” It is an iterative process that takes time, attention and effort. A process that demands significant commitment and reflection, and the ability to allow the design to evolve through restraint, simplicity, and often, the act of removal.”

Brian Cook

Brian Cook

Technical Principal of Architecture, Laboratory Planning and Interiors

Get to know Brian

  • 23 +

    years of experience in architecture

  • 20 M+

    square feet of civic, commercial mixed-use development and life-science projects delivered worldwide

  • 70 +

    LEED Gold certified projects across global markets

  • 6

    LEED Platinum certified projects across global markets

Driving innovation in life sciences and workplace design

Brian’s impact is visible in the life sciences industry, where he leads projects with highly technical workplace and laboratory environments designed to advance research, collaboration and employee wellbeing.

CRISPR Therapeutics – Research & Development Headquarters, South Boston, MA

Brian was the principal-in-charge for the CRISPR Therapeutics new research and development headquarters. This new 263,500-square-foot, seven-story research and development facility redefines how people interact at work and how science is supported through design. The project recently received the New England International Interior Design Association Award in the Science & Research category.

400 Guest Street, Allston Yards – Boston, MA

Brian oversaw the creation of a 630,000-square-foot life sciences campus targeting LEED Gold, integrating retail, community spaces and advanced mechanical systems to support next-generation research.

350 Assembly Row – Somerville, MA

At Assembly Row, Brian directed the development of a 484,700-square-foot office and life sciences building designed for flexibility and scale. The seven-story structure with 91,000 square feet combines laboratory and office space with ground-floor retail and two levels of below grade parking. A two-story enclosed mechanical penthouse adds 80,000 square feet of specialized infrastructure, ensuring the building meets the complex demands of modern research.

Solving complex challenges across global markets

Brian’s portfolio spans globally, with projects completed in China and South Korea and extends beyond workplace and laboratory interiors to include advanced energy, defense, high-rise development and civic projects. His portfolio includes a cutting-edge technology energy company totaling approximately 50,000 square feet across two buildings, integrating proprietary systems for research into new energy sources. He also oversaw the design of a two-bay Columbia-class submarine assembly building spanning more than 600 feet long, 300 feet wide and 140 feet tall.

Sustainability, recognition and thought leadership

In the pursuit of sustainable architecture, Brian has led numerous projects achieving LEED Gold and Platinum certifications, integrating green roofs, energy-efficient systems and resilient design strategies to meet climate challenges.

His work has been featured in multiple industry publications, highlighting his role in advancing material innovation, high-performance design and complex building systems.

Brian holds a bachelor of architecture from Roger Williams University and is a licensed architect in Massachusetts, New York, Vermont, New Hampshire, Connecticut and Rhode Island. He is an active member of the American Institute of Architects (AIA) and the National Council of Architectural Registration Boards.