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  Investment in the pharmaceutical and biotechnology industries remains robust and is becoming more global, fueled in part by the global need for vaccine manufacturing capacity. Biopharmaceutical products remain a significant area of development for many of our clients.

As companies in the pharmaceuticals industry continue to experience pressure to decrease product time-to-market, reduce costs, and increase return on investment, the types of services we provide have grown to include modular construction, consulting, and strategic planning to help our clients complete capital projects faster and more efficiently. We also integrate commissioning and validation services, helping reduce the amount of time required to introduce a new drug into the marketplace.

Furthermore, India and Eastern Europe are witnessing both increased inward investment and rapidly growing populations. Our local operations in these areas enhance our abilities to undertake projects for such investors.

Continued strong investment in the global process industries is expected in the years to come, and we remain unconditionally committed to the growth and success of our clients in the pharmaceutical and biotechnology industries.



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We provided project management services for the seven-story, 781,700-square-foot Ambulatory Clinical Building at the University of Texas M. D. Anderson Cancer Center in Houston. This fast-track design-build project won several awards, including the Design-Build Institute of America Excellence Award. Our design of the $70 million Exeter Crown and County Courts project in the U.K. received a Society of Chief Architects of Local Authorities Civic Building of the Year Award for 2005. The building holds nine courts and incorporates IT, facility management, and energy conservation features, yielding high levels of sustainability and flexibility in operation. The Los Angeles Regional Crime Laboratory-the first of its type in the U.S.- jointly houses city, county, and state forensic science facilities in a five-story, 209,080-square-foot steel structure on the campus of California State University, Los Angeles. With significant parts of Asio's office tower in Rome occupied during renovation, we worked closely with general coordinator First Atlantic RE to develop construction phasing plans that minimized disruption to operations while addressing site access, logistics, safety, and material flow. Total Petrochemicals sought our help for the expansion of two polypropylene trains we originally designed in the 1990s at their facility in La Porte, Texas. We used value engineering and our high-value design center in Mumbai, India, to achieve 8 percent savings on the project, which we completed 1 week ahead of an aggressive 20-month schedule. At the Borealis polypropylene production facility in Schwechat, Austria, we provided engineering, procurement, and construction for the Borstar PP5 Debottlenecking Project to increase capacity. Our application of value-enhancing practices during the design identified savings of 31 percent of budgeted total installed cost by reducing scope to match capacity objectives. Continuing our 40-year relationship with U.S. Borax, our feasibility and commercial evaluation capability helped maximize efficiency and contain costs on a recent expansion at the company's plant in Boron, California. For PCS Phosphate's expansion at their North Carolina site, we integrated modular construction with our design and field services to shorten the schedule by six months, mitigate local labor shortages, and improve construction safety. We designed two bridges as part of the $189.7 million Route 364 expansion project for the Missouri Department of Transportation. The Veterans Memorial Bridge, spanning the Missouri River, addressed evolving seismic codes and provided increased capacity and ductility, while minimizing the need and/or costs for future retrofits. As part of our long-term relationship with the U.K. government's Environment Agency, we designed the $14.5 million Littlestone-to-St. Mary's Bay Sea Defenses to protect the vulnerable coastline of the Romney Marsh in Kent. Our design contributed to savings of 12 percent. For the Nottinghamshire County Council in England, we managed the $58 million Mansfield-Ashfield Regeneration Route project from outline design to completion. Working in partnership with the contractor, our innovative solutions to site problems helped open the route six months ahead of schedule. In Nevada, we provide management oversight of the $170 million Reno Transportation Rail Access Corridor (ReTRAC) design-build project. Working as part of an integrated team with the City of Reno and the contractor, we are helping realize the 18-month schedule savings that the design-build delivery method provides. The cyclical nature of the pulp & paper industry challenges our clients to maintain flexible, qualified staffs to execute varying workloads in a cost-effective way. We have successfully partnered with many industry leaders, allowing them to baseline their staffs, improve operational efficiency, and reduce overhead costs. Energy costs comprise a large portion of our pulp & paper clients' operational cost structure. We specialize in developing creative zero-capital solutions that provide immediate savings. Our expertise in optimizing energy usage consistently provides significant reductions to our clients' annual energy budgets. Our papermaking process expertise includes tissue and towel, coated and uncoated fine papers, newsprint, and linerboard. We have over 100 pulp & paper process engineers serving the industry with an average of 25 years experience. Our expertise consistently delivers effective solutions that provide our clients with a competitive advantage. We were the program and construction manager for the BMW Information Technology Research Center at Clemson University's International Center for Automotive Research in South Carolina. The 84,000 square-foot facility is a collaborative, integrated information technology center focusing on vehicle diagnostics, new vehicle service concepts, and simulation methods in automotive engineering. We provided turnkey design and construction of an adaptive wall wind tunnel in England for B·A·R Honda. In comparison to traditional wind tunnel designs, this capability provides nearly 50 percent savings in capital and operational expenses and improves aerodynamic simulation accuracy. Since commencing operations in October 2005, Visteon's new climatic wind tunnel completed the range of product development and verification capabilities of its Climate Product Group on site at the Innovation Center in Kerpen, Germany. Design and construction of the facility was accomplished in close partnership with Visteon. Under our EPCM alliance with Nerefco, a BP/Chevron joint venture, we have a permanent task force on site executing capital projects in The Netherlands. Working so closely with our client allowed us to successfully build and install a new FCCU reactor within a tightly scheduled maintenance turnaround window. For 13 years, we've been providing maintenance and project services at Irving Oil's refinery in Saint John, New Brunswick. The company became the first Canadian company to win Hart Publications' For seven years, our alliance group at ExxonMobil's five-site complex in Baton Rouge, Louisiana, has provided on-site engineering and design services for projects of all sizes. By watching out for each other, our team of more than 185 people achieved over 2 million safe workhours. Over the past 7 years under our $457 million closure contract at the Rocky Flats Environmental Technology Site in Colorado, we performed numerous treatment activities. For example, our method evaluation, selection, and treatment of 30 million gallons of Americium-contaminated water saved the client over $25.5 million and met stringent stream segment standards. We received a perfect satisfaction score from the U.S. Army Corps of Engineers, New England District for their $300 million New Bedford Harbor restoration project in Massachusetts. Among the reasons the client cited were improved productivity and reduced unit costs, two of their primary objectives. For the Air Force Center for Environmental Excellence, we implemented corrective measures for PCB-contaminated structures at Cape Canaveral Air Force Station's Space Launch Complex 13 in Florida that included safely demolishing the 178-foot-tall Gantry Service Tower. By exercising significant skill in debris placement at the landfill, we saved approximately 50 percent of the anticipated cell area. At DOE's Fernald, Ohio, closure site, we designed a one-of-a-kind facility for wastes containing the highest concentrated source of radium in the world. The fully operational $400 million Silos Project is on the critical path of Fernald's closure program, which is on track for completion 6 months ahead of DOE's aggressive target. Wyeth and Genentech are engaged in a manufacturing agreement to produce Herceptin, a breast cancer treatment product, at Wyeth's facility in Andover, Massachusetts. Working closely with them, we successfully completed a fast-track biotech project to design and construct a $17 million facility retrofit in just seven months. Functioning as an integrated team, we completed the EPC portion of the project on schedule and 12 percent under budget. Our design and construction of modules for Eli Lilly and Company delivered the project six months ahead of traditional delivery methods. Combining standardized design and modular construction shortens a second, duplicate facility's overall schedule by nine months. The Glyco-Conjugate facility in Siena, Italy, strengthens Chiron's leading position in the meningitis vaccine market. On a tight schedule, we designed the plant to meet the strict rules of U.S. FDA and European EMEA Good Manufacturing Practices. Our design and construction of modules for Eli Lilly and Company delivered the project six months ahead of traditional delivery methods. Combining standardized design and modular construction shortens a second, duplicate facility's overall schedule by nine months. As part of our ongoing maintenance activities for Suncor at its Alberta, Canada, oil sands plant, we helped implement their fire recovery project in -34 to -40 degrees C conditions. We mobilized about 1,200 people, completing the work safely and enabling the plant to return to full production in 9 months. During construction of the UE-1 project for Syncrude in Canada, we erected 107 modules set above a live plant with zero disruptions and zero first aid incidents. We continue providing Scottish and Southern Energy and Statoil with program and construction management services for their $385 million underground gas storage facility and processing plant in Yorkshire, England. Slated for completion in mid-2009, work this year included drilling the first bore holes and starting the solution mining process. Using global resources in seven offices, we provide full EPCM services to BP for Project Resolution, a fast-track project to install a new mercaptans removal process plant for the Forties Pipeline System facilities between the Cruden Bay and Hound Point Marine Terminal, Scotland. Sixty percent complete, we have performed over half a million workhours with no lost-time incidents. Our long-term alliance with Kellogg generated savings in excess of $100 million using effective work processes, asset management, spend management, and innovation partnering as well as accurate, timely project execution. Stringently following our alliance-tailored work processes delivered value engineering savings of over $26 million in total projects costs for Coors' expansion of their packaging facility in Elkton, Virginia. Working closely with the in-house construction management team at Quinn Glass, our multidisciplinary designers met a tight schedule that enabled production at their Ince plant in Cheshire, England, only 18 months after installing the first foundation piles. For the SNS project, our standardization program for purchasing commodities in bulk quantities through small businesses saved more than $15 million, improved operations and maintenance performance, and reduced the spare parts inventory. We continue to deliver safety and cost improvements for the University of California's $3.5 billion National Ignition Facility at Lawrence Livermore Laboratory. Our lead role in renegotiating the mechanical contract saved $2 million on the installation of the amp cooling and process piping. At Argonne and Oak Ridge National Laboratories, we are supporting two of the five DOE Nanoscience research centers. At Argonne (shown here), we led a value engineering effort during design that identified $7 million in cost savings/reductions. At Oak Ridge, we used the suppliers and vendors pre-established for the SNS program to save more than $2 million in commodity costs and reduce construction time. We are helping SunPower expand the manufacturing capacity at their Laguna Techno Park facility in the Philippines. Our safety culture and practices led to over 800,000 workhours injury free with a peak of over 900 craft personnel onsite.